Technical Information

  • CAS no.: 1622902-68-4
  • Type: API

  • Usage: Refractory, moderate-to-severe atopic dermatitis
  • Technical description
    It is a selective inhibitor of Janus kinase 1 (JAK1) used to treat moderate to severe atopic dermatitis in adults. It works by blocking inflammatory signals, thereby reducing itching and skin lesions.
  • IUPAC name: -propano-1-solfonammide
  • Molecular formula: C14H21N5O2S
  • Molecular Weight: 323,414 g/mol
  • Class: JAK inhibitor
  • Chemical Structure: The name indicates a substituted pyrrolo[2,3-]pyrimidine core linked to a cyclobutyl ring.
  • Synonyms: PF-04965842 or PF04965842.

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