Azilsartan Medoxomil Potassium

CAS no.: 863031-24-7

Type: API

Usage: HTN

Technical description
Azilsartan medoxomil is a carboxylic ester obtained by formal condensation of the carboxy group of azilsartan with the hydroxy group of 4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one. A prodrug for azilsartan, it is used for treatment of hypertension. It has a role as an antihypertensive agent, a prodrug and an angiotensin receptor antagonist. It is a member of benzimidazoles, a carboxylic ester, an aromatic ether, a dioxolane, a 1,2,4-oxadiazole and a cyclic carbonate ester. It is functionally related to an azilsartan. It is a conjugate acid of an azilsartan medoxomil(1-).

IUPAC name: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2-(5-oxo-4H-1,2,4-oxadiazol-3-yl) phenyl]phenyl]methyl]benzimidazole-4-carboxylate.

Molecular formula: C₃₀H₂₄N₄O₈

Molecular Weight: 568.5 g/mol

Class: Angiotensin II receptor antagonists (AIIRA).

Synonyms: AZILSARTAN MEDOXOMIL – TAK 491 – TAK-491 – azilsartan medoxomilo.