Technical Information

  • CAS no.: 1297538-32-9

  • Type: API

  • Usage: Castration-resistant prostate cancer

  • Technical description
    Darolutamide is a nonsteroidal androgen receptor antagonist for the treatment of castrate-resistant, non-metastatic prostate cancer (nmCRPC). This condition occurs in the majority of patients with advanced prostate cancer who have been treated with androgen receptor antagonists. Though prior treatment for prostate cancer has been successful for these patients, the cancer eventually progresses to become resistant to existing therapies. This warrants further treatment. The goal of treatment with darolutamide is to delay the progression of prostate cancer to metastatic disease, increasing quality of life and life expectancy for those with advanced prostate cancer.

  • IUPAC name: N-[(2S)-1-[3-(3-chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide.

  • Molecular formula: C19H19ClN6O2

  • Molecular Weight: 398.8 g/mol
  • Class: Darolutamide belongs to the pharmacological class of nonsteroidal antiandrogens (androgen receptor inhibitors) and hormonal antineoplastic drugs.

  • Synonyms: ODM-201, ODM201.

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