Levosimendan

CAS no.: 141505-33-1

Type: API

Usage: Acute decompensated heart failure

Technical description
Levosimendan is a nitrile, a pyridazinone and a hydrazone. It has a role as a vasodilator agent, an anti-arrhythmia drug, a cardiotonic drug and an EC 3.1.4.17 (3′,5′-cyclic-nucleotide phosphodiesterase) inhibitor.

IUPAC name: 2-[[4-[(4R)-4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl]phenyl]hydrazinylidene]propanedinitrile.

Molecular formula: C₁₄H₁₂N₆O

Molecular Weight: 280.28 g/mol

Class: It is a positive inotropic and vasodilator (calcium-sensitizing) drug used as a short-term treatment for severe acute heart failure.

Synonyms: (R)-Simendan, OR-1259, and (-)-OR-1259.