Protamine Sulfate

CAS no.: 9009-65-8

Type: API

Usage: Medication used to reverse the effects of heparin

Technical description
Protamine sulfate is indicated for counteracting or reversing the anticoagulant effect of heparin as necessary. Such reversal may, for example, be required often before surgery; after renal hemodialysis; post open heart surgery; whenever excessive bleeding results from heparin use; and/or for the treatment of heparin overdosage, among other similar or related circumstances.

IUPAC name: Not applicable (mixture/complex protein).

Molecular formula: C₂₆₄H₄₆₀N₁₂₈O₆₅S₇

Molecular Weight: around 5 kDa (5000 Da) or ranging between 4 and 10 kDa

Class: Protamine sulfate belongs primarily to the class of antidotes and, more specifically, is a heparin antagonist.

Synonyms: Salmine sulfate, Prosulf, and variants like Protamine Sulphate, Sulfato de protamina, and Protamine sulfate salt.