Technical Information

  • CAS no.: 1350653-20-1

  • Type: API

  • Usage: Heart failure Myelosuppression (CIM)

  • Technical description
    Vericiguat is a pyrazolopyridine that is 5-fluoro-1H-pyrazolo[3,4-b]pyridine in which the amino hydrogen at position 1 has been substituted by a 2-fluorobenzyl group and the hydrogen at position 3 has been substituted by a 4,6-diamino-5-[(methoxycarbonyl)amino]pyrimidin-2-yl group. It is a soluble guanylate cyclase stimulator which is used for treatment of chronic heart failure. It has a role as a vasodilator agent, an antihypertensive agent and a soluble guanylate cyclase activator. It is a carbamate ester, an organofluorine compound, an aminopyrimidine and a pyrazolopyridine.

  • IUPAC name: methyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate.

  • Molecular formula: C19H16F2N8O2

  • Molecular Weight: 426.4 g/mol

  • Class: Belongs to the class of soluble guanylate cyclase (sGC) stimulators.

  • Synonyms: BAY-1021189, MK-1242.

All products

FOR ANY INFORMATION,
CONTACT US